P38 mitogen-activated protein kinases - significado y definición. Qué es P38 mitogen-activated protein kinases
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Qué (quién) es P38 mitogen-activated protein kinases - definición


P38 mitogen-activated protein kinases         
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. Persistent activation of the p38 MAPK pathway in muscle satellite cells (muscle stem cells) due to ageing, impairs muscle regeneration.
Mitogen-activated protein kinase         
  •  doi = 10.1126/scisignal.2003004 }}</ref> All cited examples refer to the interactions of the mammalian ERK2 protein.
  • X-ray structure of the ERK2 MAP kinase in its active form. Phosphorylated residues are displayed in red. Rendering based on pdb entry 2ERK.
  • doi-access=free }}</ref>
  • A simplified overview of MAPK pathways in mammals, organised into three main signaling modules (ERK1/2, JNK/p38 and ERK5).
  • Overview of MAPK pathways in yeast. Non-canonical components of the five known modules (mating, filamentation, hyperosmosis, cell wall integrity, sporulation pathways) are colored in blue.
  • s2cid=43848866 }}</ref>
P38 MITOGEN-ACTIVATED PROTEIN KINASES
Mitogen activated protein; MAPK cascade; MAP kinase; MAP Kinase; MAPK; Mitogen-activated protein; Map kinase kinase kinases; Mitogen-activated protein kinases; Map kinase signaling system; MAP kinases; MAP Kinases; Mitogen-activated-protein-kinases; Map kinase; Map-kinase; EC 2.7.11.24; MAP kinase cascade; ATP:protein phosphotransferase (MAPKK-activated); Plant MAPK
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e.
Mitogen-activated protein kinase kinase         
KINASE ENZYME
Mitogen-activated protein kinase kinases; MAP kinase kinase; MAPKK; MKK; MAPK/ERK kinase; MKKs; MAPK kinase; MAP2K; EC 2.7.12.2; ATP:protein phosphotransferase (MAPKKK-activated)
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK).